From Plaque Burden to Plaque Composition

Plaque burden with composition? That is the next question.

Cystatin C is Associated With Plaque Phenotype and Plaque Burden.

BACKGROUND/AIMS The relationship between carotid artery plaque burden, phenotype and serum cystatin C at normal and impaired renal function is still unclear. METHODS Demographic characteristics, carotid ultrasonography and other relevant information of 1,477 patients were collected. The association of carotid artery plaque burden, plaque phenotype with serum cystatin C was evaluated by strate...

Composition of the stable carotid plaque: insights from a multidetector computed tomography study of plaque volume.

BACKGROUND AND PURPOSE Calcification has been associated with carotid plaque stability; however, an acceptable in vivo method to define plaques based on this component remains to be developed. The purpose of our study was to compare calcified and noncalcified volumes of carotid artery culprit symptomatic plaques with asymptomatic plaques using multidetector computed tomography. METHODS We ide...

High coronary plaque load: a heavy burden.

Hydroxymethylglutaryl (HMG) CoA-reductase inhibitors, or statins, play an important role in the primary and secondary prevention of coronary heart disease. By inhibiting the enzyme HMG-CoA reductase, statins lower the production of cholesterol in the liver, resulting in lower LDL cholesterol levels. Besides lowering cholesterol levels, statin therapy slows down plaque progression and in some pa...

Ultrasonographic measure of carotid plaque burden.

a relatively high cumulative event rate at follow-up in multidetector computed tomography coronary angiographic (MDCT-CA) obstructive coronary artery disease compared with other studies, which may be due to characteristics of patients who had chest pain and positive stress tests in 43% and 29% of cases, respectively. However, the CONFIRM registry demonstrated that MDCT-CA has the best prognosti...